Biohacking has long been associated with Silicon Valley entrepreneurs and extreme self-experimenters pushing the limits of human performance. But a growing number of female biohackers are proving that longevity, cognitive enhancement, and optimised health are not just for male biohackers or those willing to experiment with the most radical interventions.
From nutrition scientists to medical doctors and genetic engineers, these women are shaping the future of longevity science. Their approach is grounded in data, personal experimentation, and a strong understanding of how lifestyle, supplementation, and cutting-edge interventions can extend healthspan.
This article explores some of the most influential female biohackers today, their key strategies for optimising health and brain function, and what can be learned from their research-backed approaches.
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Dr Rhonda Patrick
If you’ve ever gone down a rabbit hole on longevity science, you’ve probably come across Dr Rhonda Patrick. A biomedical researcher known for making complex science accessible, she dives deep into how nutrients, fasting, and heat therapy impact ageing at the cellular level. Unlike many biohackers who rely on anecdotal results, Patrick’s work is grounded in hard science, and she shares every study that backs up her recommendations.
Her key strategies:
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Time-restricted eating – She’s a strong advocate of fasting to optimise metabolism and slow ageing.
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Heat exposure (saunas) – Increases heat shock proteins, which help repair damaged cells.
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Sulforaphane (from broccoli sprouts) – Supports detoxification and may reduce brain inflammation.
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NAD+ precursors (like NMN and NR) – She’s discussed their role in cellular energy and mitochondrial function.
What to take from her approach:
If you want better metabolism, sharper brain function, and long-term cellular health, intermittent fasting, sauna use, and a nutrient-dense diet could be worth exploring.
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Elizabeth Parrish
Most biohackers push boundaries, but Elizabeth Parrish took it further by undergoing experimental gene therapy to reverse ageing. As the CEO of BioViva, she believes that ageing is a disease that can be treated, and she’s on a mission to prove it.
Parrish’s treatment targeted telomeres, the protective caps at the ends of chromosomes that shorten as we age. She claims that her therapy lengthened her telomeres, potentially slowing biological ageing. While the scientific community is still debating its effectiveness, her work is part of a larger shift towards treating ageing at the genetic level.
Her key strategies:
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Gene therapy for telomere extension – Aiming to slow biological ageing.
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Stem cell therapy – Exploring its role in regeneration and longevity.
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Longevity-focused nutrition – Following an anti-inflammatory, high-nutrient diet.
What to take from her approach:
While gene therapy isn’t exactly accessible yet, supporting cellular repair through good nutrition, reducing inflammation, and keeping an eye on future longevity research might be the smart move.
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Dr Sara Gottfried
If you think biohacking is all about fancy tech and extreme fasting, Dr Sara Gottfried would disagree. A Harvard-trained physician, she focuses on how hormones shape longevity, metabolism, and brain function, especially in women, who are often left out of the conversation.
Unlike many biohackers, she doesn’t advocate for one-size-fits-all approaches. Instead, she takes a hormone-first perspective, customising fasting windows, stress management, and supplements based on individual needs.
Her key strategies:
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Personalised fasting – Not everyone should fast the same way; she adjusts it based on metabolism and hormone levels.
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Cortisol control – Chronic stress is an ageing accelerator; she recommends ashwagandha and meditation for balance.
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Metabolic flexibility – A mix of low-carb periods and strategic refeeds to improve insulin sensitivity.
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Collagen for joint and skin health – She supports it for its role in connective tissue strength.
What to take from her approach:
If your hormones are out of balance, blindly following mainstream health trends can backfire. Tailoring fasting, diet, and stress management to your body’s signals is key.
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Mollie Eastman
Biohacking means nothing if you’re not getting quality sleep, and Mollie Eastman (formerly Mollie McGlocklin) has built an entire platform around optimising circadian rhythms. She argues that most people’s energy problems aren’t due to diet or caffeine, but poor sleep hygiene.
Eastman teaches people to treat sleep like a skill: something that can be optimised, measured, and improved.
Her key strategies:
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Circadian rhythm optimisation – Aligning light exposure, meal timing, and temperature for deeper sleep.
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Blue light blocking – Reducing artificial light at night to protect melatonin production.
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Magnesium and glycine – To enhance relaxation and deep sleep cycles.
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HRV (heart rate variability) tracking – Monitoring nervous system health to improve recovery.
What to take from her approach:
If you’re feeling sluggish despite a good diet and exercise, your sleep quality (not just duration) could be the missing piece.
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Kristin Weitzel
While most people avoid cold showers, Kristin Weitzel jumps into ice baths, and swears by it. A breathwork coach and performance specialist, she’s one of the biggest advocates of cold exposure for fat loss, recovery, and mental resilience.
Cold exposure is a well-documented biohack: it activates brown fat (which burns energy), boosts circulation, and increases dopamine levels by up to 250%. Weitzel pairs it with breathwork and metabolic strategies to improve endurance and brain function.
Her key strategies:
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Ice baths and cold showers – Activating brown fat and reducing inflammation.
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Breathwork for nervous system control – Helping manage stress and improve focus.
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Collagen for recovery – Supporting joints, skin, and connective tissue.
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Ketogenic cycling – Using low-carb phases to boost mitochondrial efficiency.
What to take from her approach:
Cold therapy is one of the most accessible biohacks, no expensive tech required. A few minutes in the cold could have lasting benefits for metabolism and resilience.
What Can You Take from These Biohackers?
What stands out across all these women is that biohacking isn’t just about chasing extremes, it’s about making science-backed adjustments that have a lasting impact. Some of their methods involve advanced therapies, but many of their approaches are completely accessible today:
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Personalise your approach – What works for one person might not work for another…hormones, metabolism, and lifestyle matter.
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Prioritise sleep – Sleep biohacking (light exposure, magnesium, HRV tracking) is one of the most powerful longevity tools.
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Stress strategically – Sauna therapy, cold exposure, and breathwork can build resilience.
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Optimise mitochondrial health – Nutrients like NMN, NAD+ precursors, and fasting can support energy production. Simply Nootropics Ageless NMN provides a direct NAD+ precursor, helping fuel mitochondria for sustained energy, cognitive function, and cellular repair.
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Collagen for longevity – Supporting joint, skin, and gut health through diet and supplementation. Simply Nootropics Vital Beauty delivers high-quality collagen peptides designed for optimal absorption, helping to maintain elasticity, reduce fine lines, and support overall tissue health, a must-have for long-term vitality.
